Does your doctor really understand
the research? This question is worth answering. Consider
this. Unless your doctor has actually taken courses in
research or statistics, the answer is probably no.
The average doc gets about 80% of
their information about new therapies from big pharmacy.
The profit margin for patented drugs in this country is
large enough to offend most reasonable people. According
to Sharon L. Davis, Federal Budget Analysts with the
U.S. Department of Commerce the average price for
Norvasc is $188.29, store cost is $0.14, which is a mark
up of about 134,493%. The point is, there is a huge
financial incentive to break the rules and present a
less than truthful picture when a research study is
published. Indeed, prosecution for falsifying data is
all too common, but there are many ways to cloud the
truth that are perfectly legal.
In most published research, the
probability that the data is accidental is written as P
(probability)=N. If N is greater than .05 (5%), the
statistics do not strongly support the ideas that the
study is trying to prove. Put another way, there should
be 95% chance or better that the data is not accidental
or the result of some influence outside the purpose of
the study.
Keep in mind, the bottom line when
considering any treatment is this. Do the benefits
outweigh the risks? An ethical, well informed doctor
should be able to help a patient answer this question.
With chronic, degenerative illness on the rise and
prescribed drug interactions responsible for 1 out of 4
hospital visits, it seems doubtful that this standard is
being met.
A useful statistic to know is the
number needed to treat(NNT). This describes how many
people must be treated for one person to benefit. The
NNT is not usually given up front in a published
research study, but simple math will yield this
statistic. Let’s use Lipitor, a popular cholesterol
reducing drug, as an example. The research shows that
for every 100 middle aged men with heart disease who
took Lipitor for over 3 years, one heart attack was
prevented, if compared to the same population group who
took a sugar pill for over 3 years. The rest of the
population showed no reduction in heart attacks. That
translates to a NNT of 100. Compare this to the NNT of
antibiotics used to treat H. Pylori( the bacteria that
causes ulcers). The NNT is 1:1 (for every 11 people who
take the drug, 10 are cured)! This benefit is observed
across general population, not just middle-aged men. It
is true that Lipitor lowers heart attacks by 36%.
Instead of 3 heart attacks per 100 with taking sugar
pills, you get 2 per 100 with taking Lipitor. Two is
about 36% (OK 33.3) less than three (NNT still 100).
This is about the same risk reduction
for heart attacks you get with fish oil. Fish oil does
not have the risk of liver damage, muscle and joint pain
you get with Lipitor. Thankfully, some enlightened
doctors are first recommending fish oil, niacin (vitamin
B3), red yeast rice, and other less toxic therapies,
before prescribing statin drugs such as Lipitor. The
profit margin on these natural therapies is a fraction
of the profit made on patented statin drugs. Follow the
money and it's easy to understand why the benefit versus
risk to the patient is often misrepresented .
Let's look at another dynamic at work
in the research world. There is a fierce turf war over
market share between the pharmaceutical and vitamin
industries. You may ask, what market do these two
industries have in common? It is true that
pharmaceuticals can do things that vitamins, minerals,
and herbs can't. The reverse is also true, but there is
a lot of common ground in between. Although both
industries benefit from research that supports their
products and may benefit from research that discredits
their rival; the drug companies enjoy financial
resources that are hundreds of times larger that those
of the vitamin industry.
There have been several news stories
recently on research that questions the effectiveness
and safety of vitamin and herbal therapies. Many of
these studies seem to contradict 30 years of previous
research. Often vitamin studies that are funded by big
pharmacy use inferior products. It's not surprising when
inferior results are obtained.
When choosing a multi-vitamin, look
for the quality of minerals and the percent of daily
value of the vitamins. Does it contain calcium carbonate
and magnesium oxide? These are the cheapest and most
poorly absorbed minerals available. Does it contain only
100% daily value? The daily value is based on outdated
research. A quality vitamin contains several hundred
percent of the daily value.
In a perfect world, a patient should
rely on their doctor to interpret the research and
suggest the right treatment. Considering all the forces
at work, patients would be wise to ask a few basic
questions. What are the risks versus the benefits of the
treatment? What is the NNT? What are the alternative
therapies? Who paid for the research studies? What do
they stand to gain from the results? What is the
probability factor? If your doctor can't answer these
questions, you should try to find the answers yourself
and then get a second opinion.