Several recent research studies
indicate that Vitamin D deficiency is extremely
widespread. It has long been known that Vitamin D is
important for calcium absorption to build strong bones.
But new studies link deficiency with Seasonal Affective
Disorder, Multiple Sclerosis, Lupus, Crohn's, Rheumatoid
Arthritis, high blood pressure, heart disease,
Psoriasis, Diabetes Mellitus, Pancreatitis,
Osteoarthritis, Fibromyalgia, Park-inson's,
Schizophrenia, and chronic pain and cancer of the colon,
breast, ovaries, prostate, cervix and bladder.
Technically Vitamin D is not a
vitamin at all, but a naturally occurring building block
for an important steroid hormone used by the body for
maintenance, repair and endocrine function (endocrine
glands secrete hormones into the blood stream). This
hormone targets over 200 human genes in many different
tissues. No wonder this substance seems to reduce the
risk of so many ailments when kept at proper levels in
the body.
What are proper levels? First we must
measure the right kind of vitamin D. That is 25 (OH) D.
Blood serum levels for a healthy person should be
between 40 and 70 ng/ml. If someone is affected by any
of the conditions mentioned above, they should maintain
the high end of this range. Levels can be determined by
blood tests.
What are vitamin D sources? About 90%
of the average person’s intake comes from sunlight. The
rest comes from food sources like oily fish, vitamin D
enriched foods such as milk and orange juice and vitamin
supplements. Things that affect sunlight exposure, and
the skin’s production of vitamin D, include latitude,
season of the year, time of day, air pollution, cloud
cover, skin color, use of sunblock, age, and area of
skin exposed. When the sun is low, ozone, clouds and air
pollution deflect the sun’s radiation and reduces the
skin’s production. This effect results in total
reduction during winter months at latitudes above 35 (
South Tennessee) and severe cutbacks anytime skies are
cloudy or polluted. Those who avoid sunlight at any
latitude are at risk of Vitamin D deficiency at any time
of the year. Dark skinned people, the elderly and the
obese face added risk because of lesser ability to
absorb sunlight and convert it to vitamin D for use in
the body. Sunblock of SPF 18 or higher decreases vitamin
D synthesis by 97.5%. Ten to 15 minutes of sun exposure
without sunblock per week makes enough vitamin D for
most people with no risk of skin cancer. Sunscreen is
recommended for periods longer than 15 minutes during
peak hours in summer months. Vitamin D toxicity has
never been reported from sunlight but is possible with
the use of supplements. Since fortified foods (including
milk) contain inadequate levels to prevent deficiency
during winter, supplements may be necessary for many
people. Toxicity, although rare, can present health
problems.
What is considered a safe dose? First
of all, vitamin D3 (cholacalciferol) is preferred over
D2 (ergocqlciferol) as it generates a 70% higher blood
level at equal doses. In general the more a person
weighs, the more vitamin D required. Since body fat
absorbs vitamin D, the obese need even more. In Canadian
studies, patients receiving 4000 IU/day produced 25(OH)
D levels averaging 44 ng/ml with no side effects other
than improved mood. Healthy adult men use up to 5,000 IU/day.
Dark skinned people, large, obese, or older people need
higher doses than fair skinned, small, thin, or young
folks. Some drugs may lower 25(OH) levels while others
may raise levels. More research is needed for drug
interactions, so patients on medications need their
levels monitored if taking more than 2,000IU/day .The
Food and Nutrition Board recommends doses of up to 2,000
IU/day for children over 1 year of age. Toddlers and
young children who don't get regular sun exposure should
take 1,000- 2,000 IU/day year round. Of course anyone
who gets 10-15 minute of full body, summer, noon-day sun
or artificial UVB radiation (tanning bed) once or twice
a week should get all the vitamin D they need. Sunburn
should be avoided to reduce the risk of Melanoma.
Regular UV exposure ages the skin and increases the risk
of all skin cancers, so remember to use sunblock for
exposure for longer than 15 minutes. Pregnant women or
those trying to conceive should have 25(OH) D levels
checked every three months and be supplemented with D3
to bring levels above 40 mg/ml. They may need up to
5,000 IU/day. Breast feeding mothers require up to 7,000
IU/day to assure their milk is rich in vitamin D.
Infants may require supplements during and after
weaning.
Although more research needs to be
done, vitamin D therapy is very promising in addition to
conventional treatment for the conditions mentioned
above. Just remember , although rare, toxicity is a
possibility. Moderate to severe cases of hypercalcenia
should avoid vitamin D therapy. Others should work with
a doctor knowledgeable in vitamin D therapy for doses
above 1,000 IU/day. Although the government Recommended
Daily Allowance is only 400 IU/day, keep in mind the RDA
values for most vitamins and minerals is based on 50
year old science and are only adequate to prevent the
more obvious conditions of deficiency known at the time.
The statistics in this article were gathered from
studies published in the Archives of Internal Medicine
and the American Journal of Clinical Nutrition to name a
few.
For further links and info on this or
any column feel free to e-mail me at totalhealth@frontiernet.net.